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Scientists from Charles River Laboratories and Curiox Biosystems collaborated to characterize the performance and workflow of Laminar WashTM systems in isolating and preparing tumor infiltrating leukocytes (TILs) from anti-PD1-challenged CT26 mice, as a model system.
Compared to conventional centrifuge-based methods, Laminar Wash technology:
- Improved recovery of viable TILs from dissociated tumors
- Reduced inter-operator variation in TIL recovery
- Shortened labor-intensive hands-on washing steps